For healthy men and non-pregnant women, a normal Alpha-fetoprotein (AFP) count typically ranges from 10 ng/mL to 20 ng/mL.
Understanding Alpha-fetoprotein (AFP)
Alpha-fetoprotein (AFP) is a protein primarily produced by the liver and yolk sac of a developing baby during pregnancy. In adults, AFP levels are usually very low, and its presence or elevation can be an important indicator in health screenings.
Normal AFP Levels Explained
The normal range for Alpha-fetoprotein (AFP) varies significantly depending on an individual's physiological state. Based on established guidelines, specific ranges apply:
| Group | Normal AFP Range (as per reference) |
|---|---|
| Healthy Men | 10 ng/mL to 20 ng/mL |
| Non-Pregnant Women | 10 ng/mL to 20 ng/mL |
It is crucial to understand that this specific normal range applies explicitly to healthy men and non-pregnant women.
What Elevated AFP Levels May Indicate
Higher than normal AFP levels can be a marker for various health conditions, and the interpretation differs significantly between pregnant and non-pregnant individuals.
During Pregnancy
In pregnant individuals, elevated AFP levels require further investigation as they could suggest:
- Neural abnormalities: Such as spina bifida, where the spinal cord does not close properly.
- The presence of twins: As multiple fetuses produce more AFP, leading to naturally higher levels.
In Men and Non-Pregnant Women
For healthy men and non-pregnant women, AFP levels that are higher than the normal range (above 10 ng/mL to 20 ng/mL) could indicate:
- Ovarian cancer
- Liver cancer
- Lymph node cancers
- The recurrence of previous tumors.
