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What is the difference between Purkinje fibers and Purkinje cells?

Published in Anatomical Structures 2 mins read

Purkinje fibers and Purkinje cells are distinct structures found in different parts of the body with different functions.

Key Differences Between Purkinje Fibers and Purkinje Cells

Feature Purkinje Fibers Purkinje Cells
Location Heart tissue Cerebellum of the brain
Function Cardiac conduction Neurotransmission, specifically inhibition
Primary Role Rapidly transmit electrical impulses for synchronized heart contractions Release GABA to inhibit nerve conduction
Neurotransmitter Not Applicable Gamma-aminobutyric acid (GABA)
Effect Coordinates ventricular contraction Blocks nerve conduction in the postsynaptic membrane

Purkinje Cells Explained

Purkinje cells are a type of neuron found in the cerebellum, a part of the brain responsible for motor control, learning, and coordination. They are known for their large size and elaborate dendritic arbors, which resemble a fan. The primary function of Purkinje cells is to act as inhibitory neurons within the cerebellar cortex. They achieve this by releasing the neurotransmitter gamma-aminobutyric acid (GABA).

  • GABA Release: When a Purkinje cell is activated, it releases GABA, which travels across the synapse to bind with receptors on the postsynaptic membrane.
  • Inhibitory Effect: The binding of GABA leads to the inhibition of nerve conduction in the postsynaptic neuron.
  • Contribution to Coordination: This inhibitory activity plays a crucial role in fine-tuning motor movements and ensuring smooth and coordinated actions.

Purkinje Fibers Explained

Purkinje fibers are specialized myocardial muscle fibers that are part of the heart's electrical conduction system. They are located in the ventricles and ensure that the electrical impulse is distributed evenly and quickly throughout the heart muscle to cause synchronized ventricular contractions.

  • Electrical Conduction: Purkinje fibers are the final part of the heart’s electrical conduction system and are specialized to rapidly conduct electrical signals.
  • Synchronized Contraction: The rapid transmission of electrical impulses ensures that the ventricular muscles contract in a synchronized manner, pumping blood effectively out of the heart.
  • Location: These fibers are located in the inner ventricular walls, just beneath the endocardium.
  • Function: These fibers are essential for coordinating the heart’s contractions.

Summary

In short, Purkinje cells are neurons in the brain responsible for inhibition, whereas Purkinje fibers are part of the heart's electrical conduction system, ensuring synchronized contractions. One is a component of the nervous system, specifically in the brain, while the other is a component of the cardiovascular system, specifically in the heart.