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What is NAM disease?

Published in Autoimmune Myopathy 1 min read

NAM disease refers to Necrotizing Autoimmune Myopathy (NAM), also known as Immune-Mediated Necrotizing Myopathy (IMNM). It's a condition marked by muscle cell death (necrosis), leading to muscle weakness and fatigue.

Understanding Necrotizing Autoimmune Myopathy (NAM)

NAM is characterized by the following:

  • Necrosis: The defining feature is the death of muscle cells. This necrosis causes inflammation and damage within the muscle tissue.
  • Autoimmune: It's an autoimmune condition, meaning the body's immune system mistakenly attacks its own muscle tissue.
  • Myopathy: This refers to a disease of the muscles, resulting in weakness and impaired function.

Key Characteristics of NAM/IMNM

Feature Description
Primary Symptom Muscle weakness
Underlying Cause Autoimmune attack on muscle cells
Cellular Damage Necrosis (muscle cell death)
Other Names Necrotizing Autoimmune Myopathy (NAM), Immune-Mediated Necrotizing Myopathy (IMNM)
Common Symptoms Fatigue