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What Autoimmune Disease Causes Autonomic Neuropathy?

Published in Autoimmune Neuropathy 2 mins read

Certain autoimmune diseases, notably lupus and rheumatoid arthritis, are known to cause autonomic neuropathy by inducing nerve damage that affects the body's involuntary functions.

Understanding Autonomic Neuropathy

Autonomic neuropathy is a condition that occurs when the nerves that control involuntary body functions are damaged. These nerves are part of the autonomic nervous system, which manages essential functions like:

  • Heart rate
  • Blood pressure
  • Digestion
  • Urination
  • Body temperature regulation

When these nerves are compromised, it can lead to a wide range of symptoms affecting multiple body systems.

Autoimmune Links to Autonomic Nerve Damage

Autoimmune diseases develop when the body's immune system mistakenly attacks its own healthy tissues, viewing them as foreign invaders. In some cases, this misguided immune response can target components of the nervous system, including the autonomic nerves. The inflammation and damage caused by this autoimmune activity can disrupt nerve signals, leading to autonomic neuropathy.

Specific autoimmune conditions recognized for their potential to cause autonomic neuropathy include:

  • Lupus (Systemic Lupus Erythematosus): This chronic inflammatory disease can affect various organs and tissues, including the nervous system. When lupus impacts nerves, it can lead to neuropathy, specifically targeting autonomic functions.
  • Rheumatoid Arthritis: Primarily known for causing inflammation in the joints, rheumatoid arthritis can also have systemic effects. The chronic inflammation and immune dysregulation associated with RA can contribute to nerve damage, manifesting as autonomic neuropathy.

While diabetes is a common cause of autonomic neuropathy, it's crucial to understand that autoimmune diseases also represent significant risk factors for developing this condition. The nerve damage induced by these autoimmune responses can profoundly impact a person's quality of life, necessitating proper diagnosis and management of both the underlying autoimmune disease and the resulting neuropathy.