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What is Propionibacterium acnes (P. acnes)?

Published in Bacterial Skin Flora 2 mins read

Propionibacterium acnes (P. acnes) is a type of bacteria commonly found on the skin, particularly in areas rich in sebaceous glands.

Understanding Propionibacterium acnes

P. acnes is a bacterium that resides on human skin and plays a role in skin health and conditions like acne. Here's a detailed look at its characteristics and where it's found:

Characteristics of P. acnes

Feature Description
Shape Rod-shaped
Growth Slow-growing
Type Gram-positive, Anaerobe (thrives in environments without oxygen)
Spore Non-spore forming
Habitat Found across various body sites, especially in sebaceous follicles of the face and neck.
Ubiquity Ubiquitous (present virtually everywhere on the human body)

Where P. acnes is Found

  • P. acnes is commonly found on human skin, thriving in areas with a high density of sebaceous glands. These glands produce sebum, an oily substance that helps keep the skin moisturized.
  • Key locations include:
    • Sebaceous follicles: These are tiny structures in the skin where hair grows and sebum is produced. They are most abundant on the face, neck, chest, and back.
    • Other body sites: P. acnes can also be found in smaller numbers in other areas, including the scalp, arms, and legs.

Insights into P. acnes

  • P. acnes is considered a commensal bacterium, meaning it normally lives on the skin without causing harm. In fact, it may play a beneficial role in maintaining skin health by:
    • Preventing colonization by harmful bacteria: P. acnes can outcompete other, potentially harmful bacteria for resources, helping to prevent infections.
    • Contributing to skin's acidic pH: P. acnes produces fatty acids that help maintain the skin's slightly acidic pH, which is important for its barrier function.
  • However, under certain conditions, P. acnes can contribute to the development of acne. This can happen when:
    • Sebum production increases: Excess sebum can create an environment that promotes the overgrowth of P. acnes.
    • Follicles become blocked: Dead skin cells and sebum can clog the hair follicles, trapping P. acnes inside.
    • Inflammation occurs: The immune system may react to the increased P. acnes and trapped sebum, leading to inflammation and the formation of acne lesions.