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Is CBC a Biomarker?

Published in Biomarkers 2 mins read

The answer depends on what "CBC" refers to.

If "CBC" refers to a Complete Blood Count, then yes, it is a biomarker.

Understanding Biomarkers and Complete Blood Counts

A biomarker is a measurable indicator of a biological state or condition. Biomarkers can be used to assess normal biological processes, pathogenic processes, or responses to a therapeutic intervention.

A Complete Blood Count (CBC) is a common blood test that evaluates the cells in your blood:

  • Red blood cells (RBCs): Carry oxygen.
  • White blood cells (WBCs): Fight infection.
  • Platelets: Help with blood clotting.

CBC as a Biomarker: In Detail

Since the CBC measures components of blood that can indicate various health conditions, it directly qualifies as a biomarker. Abnormalities in the CBC results (e.g., elevated white blood cell count, low hemoglobin) can indicate infection, anemia, bleeding disorders, and other conditions. Doctors frequently use CBC results to screen for, diagnose, and monitor a wide range of diseases.

For example:

  • Elevated WBC count: Can indicate an infection or inflammation.
  • Low RBC count: Can indicate anemia.
  • Low platelet count: Can indicate a bleeding disorder.

What if CBC refers to The Circulating Biomarker Core?

If "CBC" refers to The Circulating Biomarker Core, then it is an entity or facility that develops and translates circulating biomarker assays. Therefore, The Circulating Biomarker Core itself is NOT a biomarker, but it works with biomarkers.

Conclusion

In summary, if "CBC" refers to a Complete Blood Count, it is indeed a biomarker. However, if "CBC" refers to The Circulating Biomarker Core, it is an organization that deals with biomarkers, but is not a biomarker itself.