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Is Donating AB+ Blood Useful?

Published in Blood Donation 2 mins read

Yes, donating AB+ blood is extremely useful.

Why is AB+ Blood Donation Important?

AB+ blood type is unique due to the antigens present on the red blood cells, but more importantly because it results in unique plasma characteristics. The key utility of AB+ blood lies in its plasma.

  • Universal Plasma Donor: According to the reference, "Donors who are AB-positive are considered the universal plasma donors."
    This means that AB+ plasma can be safely transfused into recipients of any blood type (A+, A-, B+, B-, AB+, AB-, O+, and O-) without causing a transfusion reaction. This is because the plasma lacks anti-A and anti-B antibodies.

Benefits of AB+ Plasma

The wide compatibility of AB+ plasma makes it vital in several clinical situations.

  • Emergency Situations: In trauma or emergencies, when the recipient's blood type is unknown or when there isn't enough time to check, AB+ plasma can be administered safely to prevent life-threatening issues.

  • Treatment for Bleeding Disorders: AB+ plasma, with its coagulation factors, can be used to manage bleeding in patients with clotting factor deficiencies.

  • Other Uses: It also has use in treatments such as plasma exchange therapies where plasma is separated from blood.

The Importance of Understanding Blood Types


Blood Type Red Cell Compatibility (Donation) Plasma Compatibility (Donation)
A+ A+, AB+ A+, A-, O+, O-
A- A+, A-, AB+, AB- A-, O-
B+ B+, AB+ B+, B-, O+, O-
B- B+, B-, AB+, AB- B-, O-
AB+ AB+ Universal (All types)
AB- AB+, AB- AB-, A-, B-, O-
O+ O+, A+, B+, AB+ O+, O-
O- Universal (All types) O-


Understanding the compatibility of blood types helps ensure safe blood transfusions and optimal treatment for patients. AB+ individuals are encouraged to donate because their plasma is so valuable.