A TNC cell refers to a Total Nucleated Cell. In the context of bone marrow transplantation, the total nucleated cell count is a crucial factor.
Importance of TNC Count in Bone Marrow Transplantation
According to the provided reference, the total nucleated cell (TNC) count per recipient body weight is an important factor predicting engraftment following bone marrow transplantation. This means that a higher TNC count is generally associated with a better chance of successful engraftment, where the transplanted cells establish themselves and start producing new blood cells in the recipient's body. The reference also indicates that larger TNC counts can be obtained by harvesting larger volumes of bone marrow.
| Feature | Description |
|---|---|
| TNC | Total Nucleated Cell |
| Importance | Predicts engraftment success after bone marrow transplantation |
| Higher TNC count | Generally leads to better engraftment |
| Collection | Achieved by harvesting larger volumes of bone marrow |
