zaro

What is the pH of the Brain?

Published in Brain pH 1 min read

The pH of the brain is generally in the range of 7.2 to 7.4. This range varies slightly depending on whether you're measuring the extracellular or intracellular environment.

Understanding Brain pH

Maintaining a stable pH in the brain is critical for its proper function. Significant deviations from the normal range can impair neuronal activity and lead to various neurological disorders.

Extracellular vs. Intracellular pH

  • Extracellular pH: Studies show that the resting or physiological extracellular brain pH typically falls within the range of 7.2–7.4.
  • Intracellular pH: The intracellular pH tends to be slightly lower than the extracellular pH.
Measurement pH Range
Extracellular Brain pH 7.2-7.4
Intracellular Brain pH Slightly lower than 7.2-7.4