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Do Brain Cells Regrow?

Published in Brain Regeneration 2 mins read

Yes, brain cells can regrow, but not in the same way as skin cells. This process, called neurogenesis, involves the brain using neural stem cells to create new neurons. It's a unique method, different from simple cell division (mitosis), and occurs primarily when brain areas are damaged.

Understanding Neurogenesis

Neurogenesis isn't widespread throughout the entire brain, but research shows it does occur in specific regions like the hippocampus, a crucial area for memory and learning. While the adult brain has limited stem cell capacity, concentrated in small regenerative zones, these cells can be prompted to create new neurons under specific conditions. Harvard Health and Verywell Mind discuss the process and limitations of adult neurogenesis. The brain’s ability to repair itself by reverting to a less mature state, enabling axon regrowth in a supportive environment, is another aspect of this process. UCSD Health provides insight into this adaptive mechanism.

How it Differs from Other Cell Regeneration

Unlike skin cells which readily regenerate through mitosis, neurons typically don't replace themselves in the same way. However, studies show that specific proteins and environmental conditions can trigger neurogenesis in the adult brain. UT Southwestern highlights the role of a single protein in prompting this regeneration. The central nervous system's injured nerve cells generally do not regenerate, although reorganization can occur. Mayo Clinic points out this difference.

Practical Implications and Limitations

While neurogenesis is a promising area of research, it's not a complete solution for all brain injuries or diseases. The extent of regeneration is limited, and its precise mechanisms are still being explored. The brain's ability to compensate for damage through recruitment of existing neurons is another important factor. UCLA Health describes this compensation mechanism. Furthermore, not all brain cells regenerate; for instance, once eye cells die, they can't be regenerated. NIH clarifies this limitation.