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What is a CTC blood test?

Published in Cancer Blood Test 2 mins read

A CTC blood test, specifically the CELLSEARCH® CTC Test, is a blood test that helps oncologists assess the prognosis of patients with metastatic breast, prostate*, or colorectal cancer.

Understanding the CTC Blood Test

The CELLSEARCH® CTC Test is significant because it is:

  • A simple blood test: It's easily performed, requiring only a blood sample.
  • Actionable: The results provide valuable information for treatment planning.
  • Clinically validated: The test has undergone rigorous testing and has demonstrated accuracy in its findings.
  • FDA-cleared: The U.S. Food and Drug Administration has approved the test for clinical use.
  • Focused on Circulating Tumor Cells (CTCs): It specifically measures the number of CTCs present in a patient's blood. These are cancer cells that have detached from the primary tumor and are circulating in the bloodstream.

How Does the CTC Blood Test Work?

The CELLSEARCH® CTC Test:

  1. Obtains a blood sample from the patient.
  2. Analyzes the sample to identify and count the number of circulating tumor cells (CTCs).
  3. Provides a numerical result indicating the quantity of CTCs in the patient's bloodstream.

What are Circulating Tumor Cells (CTCs)?

  • CTCs are cancer cells that have broken away from the primary tumor.
  • They circulate through the bloodstream and can potentially travel to other parts of the body, leading to the formation of new tumors (metastasis).
  • The presence and quantity of CTCs can provide valuable insights into the aggressiveness of cancer and its potential to spread.

Why is Measuring CTCs Important?

  • Prognosis: The number of CTCs can help oncologists determine the likely course of the cancer. Higher numbers often indicate a poorer prognosis.
  • Treatment Monitoring: Changes in CTC counts over time can help monitor the effectiveness of cancer treatments. A decrease in CTCs may indicate that treatment is working, while an increase might suggest that the cancer is progressing or not responding to the therapy.

Key Features of the CELLSEARCH® CTC Test:

Feature Description
Type Blood Test
Target Circulating Tumor Cells (CTCs)
Application Prognostic assessment for metastatic breast, prostate*, or colorectal cancer
Status Clinically validated and FDA-cleared

Conclusion

The CTC blood test, particularly the CELLSEARCH® CTC Test, provides a simple yet powerful way for oncologists to assess the prognosis of patients with metastatic cancer. By measuring CTCs in the bloodstream, it offers valuable information for treatment planning and monitoring.