When Enhertu (trastuzumab deruxtecan) is no longer effective, your healthcare team will evaluate new treatment strategies tailored to your specific condition and cancer characteristics.
Tailoring Your Next Steps in Treatment
Determining the appropriate course of action after Enhertu is a highly individualized process, guided by your oncologist and healthcare team. This decision is made after careful consideration of several factors to ensure the most effective and personalized treatment plan.
Key considerations often include:
- Type of Cancer: The specific cancer type and its stage.
- Previous Treatments: How you responded to Enhertu and other prior therapies.
- Tumor Characteristics: Re-evaluation of the tumor's genetic makeup and HER2 status, as these can change over time.
- Overall Health and Performance Status: Your general health, kidney and liver function, and ability to tolerate new treatments.
- Side Effects: Any lingering side effects from previous treatments.
Potential Treatment Considerations
After Enhertu stops working, your doctor may consider various options. One potential treatment your doctor may discuss is Herceptin (trastuzumab). This treatment might be considered suitable for certain cases, and your doctor will determine if it aligns with your specific needs and the characteristics of your cancer.
Other potential avenues that might be explored could include:
- Other Targeted Therapies: If specific genetic mutations or protein expressions are identified.
- Chemotherapy: Traditional chemotherapy regimens may be considered.
- Immunotherapy: Depending on the cancer type and specific biomarkers.
- Clinical Trials: Participation in clinical trials testing new and experimental therapies may also be an option, providing access to cutting-edge treatments.
The Importance of Ongoing Communication
Maintaining open and continuous dialogue with your oncology team is crucial as you navigate treatment decisions after Enhertu. They are the best resource for understanding your specific case and the most suitable next steps.
Here's what to discuss with your doctor:
- Your current symptoms and side effects.
- Any concerns or questions you have about your treatment options.
- The potential benefits and risks of each recommended therapy.
- Whether clinical trials are a viable option for you.
- Your personal preferences and goals for treatment.
Your personalized treatment path will be decided in collaboration with your healthcare providers, focusing on the best possible outcome for your unique situation.