COPP is not a disease itself, but rather a chemotherapy regimen used to treat Hodgkin's lymphoma (Hodgkin's disease). It's a combination of four drugs: Cyclophosphamide, Oncovin (vincristine), Procarbazine, and Prednisone. The combination is designed to kill cancer cells. Several studies have compared COPP to other chemotherapy regimens in treating advanced Hodgkin's disease, such as COPP-ABVD and BEACOPP. [See references](https://pubmed.ncbi.nlm.nih.gov/12802024/, https://www.nejm.org/doi/abs/10.1056/NEJMoa022473, https://pubmed.ncbi.nlm.nih.gov/9137793/, https://en.wikipedia.org/wiki/COPP_(chemotherapy), https://www.cancer.gov/about-cancer/treatment/drugs/copp, https://link.springer.com/article/10.1007/BF00396383, https://www.sciencedirect.com/science/article/pii/S0923753419656085).
It's important to distinguish COPP (chemotherapy) from Cryptogenic Organizing Pneumonia (COP), an entirely different condition. COP is a form of interstitial lung disease causing inflammation of the small airways and alveoli, resulting in breathing difficulties and flu-like symptoms. See reference. The abbreviation "COPP" in the context of cancer treatment refers exclusively to the chemotherapy regimen.
Key Aspects of COPP Chemotherapy:
- Drug Combination: Cyclophosphamide, Oncovin (vincristine), Procarbazine, and Prednisone.
- Use: Treatment of Hodgkin's lymphoma.
- Studies: Numerous studies have evaluated its efficacy and compared it to other treatments.
- Distinct from COP: Not to be confused with Cryptogenic Organizing Pneumonia (COP), a lung disease.
