zaro

Is it better to give Apoquel in the morning or at night?

Published in Canine Allergy Medication 3 mins read

It is generally advised to give Apoquel in the morning. However, for maintenance doses, your veterinarian may recommend splitting the administration to twice a day, which would include both morning and night doses.

Apoquel (oclacitinib) is a targeted therapy commonly prescribed by veterinarians to help control itching associated with allergic dermatitis in dogs. Understanding the best time to administer this medication can enhance its effectiveness and your pet's comfort.

Morning Administration: The Primary Recommendation

For many dogs, particularly when starting treatment or on a once-daily regimen, giving Apoquel in the morning is the preferred approach. This timing can align with the dog's daily activity cycle and help manage itch when it might be most bothersome during waking hours.

Maintenance Dosing: Flexibility and Effectiveness

While a morning dose is often recommended, the approach can vary for long-term management:

  • Split Dosing: For maintenance, a veterinarian might advise splitting the daily dose into two administrations (twice a day). This means your dog would receive a dose in the morning and another in the evening or at night. This strategy aims to maintain consistent drug levels in the body, which can be beneficial for controlling persistent itch.
  • Target Dosage: When managing chronic itch, veterinarians may adjust the maintenance dose to be closer to 0.6 mg/kg to ensure optimal efficacy.

Complementary Treatments and Timing

The timing of other medications can also play a role in a comprehensive itch management plan. For instance, if your dog is also prescribed diphenhydramine (an antihistamine), it might be advised to give this medication at night due to its potential sedative effects, complementing the morning Apoquel dose.

Summary of Administration Timings

Medication Recommended Timing Purpose/Benefit
Apoquel Morning (initial) Addresses daytime itching, aligns with active hours
Apoquel Morning & Night (maintenance) Maintains consistent drug levels for chronic itch control
Diphenhydramine Night Manages evening itch, potential sedation can aid sleep

Important Considerations for Pet Owners

  • Always Follow Veterinary Advice: The most crucial aspect of administering Apoquel or any medication is to strictly follow your veterinarian's specific instructions. They tailor the dosage and timing to your dog's individual needs, weight, and the severity of their condition.
  • Consistency is Key: Regardless of whether your dog is on a once-daily morning dose or a twice-daily split dose, consistency is vital for effective itch control. Try to administer the medication at the same time(s) each day.
  • Monitor Your Dog: Pay close attention to your dog's response to the medication. If you notice any side effects or if the itching is not well-controlled, contact your veterinarian.
  • Never Self-Medicate: Do not adjust the dosage or timing of Apoquel without consulting your vet. Incorrect dosing can lead to reduced efficacy or potential side effects.

For further information on managing allergic dermatitis, consulting professional veterinary resources like those from dvm360.com can provide valuable insights.