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Can you use normal saline with Cathflo?

Published in Catheter Care 3 mins read

Yes, normal saline is used in conjunction with Cathflo, specifically for irrigating the catheter after Cathflo Activase has been administered and its effects completed.

Understanding the Role of Normal Saline with Cathflo Activase

Cathflo Activase (Alteplase) is a medication primarily used to restore patency to occluded central venous access devices (CVADs). While Cathflo Activase directly works to dissolve clots within the catheter, normal saline plays a crucial role in the post-treatment management of the catheter. It is not typically used to dilute or administer Cathflo Activase itself, but rather to ensure the catheter is clear and functioning properly after the clot dissolution process.

Post-Treatment Catheter Care with Normal Saline

After Cathflo Activase has had time to act and catheter function has been successfully restored, normal saline is vital for clearing the catheter of any remaining medication or debris. This process helps maintain the catheter's patency and prepares it for subsequent use.

The specific steps involving normal saline after Cathflo Activase treatment typically include:

  1. Aspiration: Once catheter function is restored, 4-5 ml of blood should be aspirated from the catheter. This step is critical to remove the Cathflo Activase medication and any residual clot fragments from the catheter lumen.
  2. Irrigation: Following aspiration, the catheter should be gently irrigated with 10 ml of normal saline. This flush helps to thoroughly clear the line, ensuring that all medication and clot debris are removed, and the catheter is clean for future use.

Why Normal Saline is Important for Post-Cathflo Flushing

Normal saline (0.9% sodium chloride) is the standard solution used for flushing central venous catheters due to its isotonic nature, which is compatible with the body's fluids. Its use after Cathflo Activase treatment ensures:

  • Removal of Residual Medication: Flushes out any remaining Cathflo Activase, preventing prolonged exposure or systemic effects.
  • Clearance of Clot Debris: Helps to dislodge and remove any small clot fragments that may still be present after aspiration.
  • Maintenance of Patency: Prepares the catheter for immediate or future use by ensuring a clear lumen.

Key Aspects of Normal Saline Use with Cathflo

To clarify the precise application, here's a summary:

Aspect Description
Purpose of Use To irrigate and clear the catheter after Cathflo Activase treatment has successfully restored patency.
Timing Used after Cathflo Activase has acted and been aspirated from the catheter.
Volume Typically, 10 ml of normal saline is used for irrigation.
Method Administered via gentle irrigation after aspiration of blood and residual Cathflo/clot.
Compatibility Normal saline is highly compatible for flushing, helping to maintain catheter integrity.

In summary, while normal saline is not used to administer Cathflo, it is an integral part of the overall procedure to ensure effective and safe post-treatment catheter management.