Keratocytes are specialized cells found in the cornea of the eye.
Detailed Explanation of Keratocytes
Here's a more in-depth look at these important cells:
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Origin and Location: Keratocytes are neural-crest derived mesenchymal cells and they sparsely populate the corneal stroma.
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Normal State: In their normal state, keratocytes are quiescent, meaning they are relatively inactive. They have a dendritic (branch-like) shape.
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Response to Injury: When the cornea is injured, keratocytes are stimulated. They can then either:
- Undergo apoptosis (programmed cell death).
- Transition into repair phenotypes, contributing to the healing process.
In summary, keratocytes are crucial for maintaining the health and integrity of the cornea. They are normally dormant but become active when the cornea is damaged.
