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What are septal cells?

Published in Cell Biology 2 mins read

Septal cells, also known as type II alveolar cells, are a vital component of the lung's alveoli. They play a crucial role at the alveolar-capillary barrier. Here's a breakdown of their characteristics and importance:

Key Features of Septal Cells

  • Location: Septal cells are primarily located at the alveolar-capillary barrier within the lungs. This strategic position allows them to perform their essential functions effectively.
  • Abundance: They constitute nearly 60% of the alveolar epithelial cells, making them the most numerous cell type in this region.
  • Secretion of Surfactant: The most crucial function of septal cells is to produce and secrete a substance called surfactant. This is a surface-active lipoprotein complex that is key to proper lung function.

Why is Surfactant Important?

Surfactant is critical for reducing surface tension within the alveoli.

  • Reduces surface tension: By reducing surface tension, surfactant prevents the alveoli from collapsing during exhalation.
  • Ensures gas exchange: Proper alveolar inflation and deflation allow for efficient gas exchange between the air and the blood, which is vital for respiration.
  • Supports lung health: Without adequate surfactant, the lungs would require significantly more effort to inflate, potentially leading to respiratory distress.

Septal Cells: A Summary

Feature Description
Other name Type II alveolar cells
Location Alveolar-capillary barrier
Quantity About 60% of alveolar epithelial cells
Main function Secrete surfactant, which reduces surface tension in alveoli for proper lung function.

In conclusion, septal cells are essential for maintaining the structural integrity and functional efficiency of the lungs. Their ability to produce surfactant is fundamental to healthy respiration.