Based on the provided reference, long-term hematopoietic stem cells are among the rarest cells in the human body.
Here's a breakdown:
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Long-Term Hematopoietic Stem Cells (LT-HSCs): These cells are crucial because they can completely regenerate the bone marrow and hematopoietic (blood-forming) system.
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Rarity: The reference indicates just how rare they are. In mice, LT-HSCs constitute only 0.00019% of the cells in the bone marrow. While the exact percentage may vary in humans, it underscores their extreme scarcity.
In summary, while there may be other extremely rare cell types in the human body, the provided reference specifically highlights the rarity of long-term hematopoietic stem cells and their importance in the human body.