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What is a Progenitor Cell?

Published in Cell Biology 2 mins read

A progenitor cell is a type of biological cell that can differentiate into a specific, defined cell type.

Understanding Progenitor Cells

Progenitor cells are similar to stem cells in their ability to differentiate into various cell types. However, a key difference lies in their specificity and self-renewal capacity. According to the provided reference, while both stem cells and progenitor cells can differentiate into specific cell types, stem cells are less specified than progenitor cells.

Key Differences Between Stem Cells and Progenitor Cells

To better understand progenitor cells, it's helpful to compare them with stem cells:

Feature Stem Cell Progenitor Cell
Differentiation Can differentiate into many cell types. Differentiates into a specific cell type.
Self-Renewal High self-renewal capacity. Limited self-renewal capacity.
Specification Less specified. More specified.

Essentially, progenitor cells are "daughter" cells of stem cells that are already committed to becoming a particular cell type. The provided reference explicitly states that progenitor cells can only differentiate into their "target" cell type.

Examples of Progenitor Cells

Here are some examples of progenitor cells and their "target" cell types:

  • Myeloid progenitor cells: Differentiate into various blood cells, such as red blood cells, platelets, and certain types of white blood cells.
  • Neural progenitor cells: Differentiate into different types of brain cells, such as neurons and glial cells.

In summary, progenitor cells are crucial for tissue repair, development, and maintenance due to their ability to differentiate into specific cell types.