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What happens in mitosis?

Published in Cell Division 2 mins read

Mitosis is a fundamental process where a single cell's nucleus divides, creating two identical daughter nuclei. Here's a detailed breakdown of what occurs during this crucial phase of the cell cycle, based on the provided reference:

The Stages of Mitosis

Mitosis is more than a simple splitting; it's a carefully choreographed series of events, where chromosomes are replicated then accurately separated and distributed into two daughter cells. According to our reference, the key steps are:

  • Chromosome Condensation: The initially long, thin chromosomes coil and condense, becoming more visible and manageable for separation.
  • Nuclear Envelope Breakdown: In most cells, the membrane surrounding the nucleus, known as the nuclear envelope, breaks down. This allows the chromosomes access to the mitotic spindle.
  • Mitotic Spindle Formation: The cytoskeleton, the cell's internal framework, reorganizes to form the mitotic spindle. The spindle is crucial for aligning and moving chromosomes.
  • Chromosome Movement: The spindle fibers attach to the chromosomes, facilitating their movement to opposite poles (ends) of the cell.

Steps in Chromosome Separation

These phases ensure each daughter cell receives an exact copy of the parent cell's genetic material:

  1. Alignment at the Metaphase Plate: Chromosomes line up in the middle of the cell, a process which is not detailed in the reference provided, but is still important in mitosis.
  2. Separation and Segregation: The duplicated chromosome copies, now called sister chromatids, are then pulled apart and move to opposite poles.
  3. Formation of Daughter Nuclei: After chromosome separation (segregation), nuclear envelopes begin to reform around the separated chromosomes to form two distinct nuclei.

Following Mitosis: Cytokinesis

After mitosis, the cell usually proceeds to cytokinesis, which is the physical separation of the cell into two daughter cells, as mentioned in the reference.

Summary in Table Format

Process Description
Chromosome Condensation Chromosomes become shorter and thicker.
Nuclear Envelope Breakdown The membrane around the nucleus disintegrates.
Mitotic Spindle Formation The cell's framework forms a structure for chromosome movement.
Chromosome Movement to Opp Poles Chromosomes are pulled to opposite ends of the cell by the spindle fibers.
Cytokinesis Typically follows, dividing the cell into two separate daughter cells, though not detailed in the provided reference

Mitosis, therefore, is a very precise process. It is important to cell function because it makes sure that each cell after division contains the same genetic information.