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How do cells maintain water?

Published in Cellular Hydration 1 min read

Cells maintain water balance through a sophisticated mechanism, partly by organizing their internal environment.

According to research published in Nature, a key mechanism involves redistributing proteins into fluid assemblies called biomolecular condensates. This process helps manage the availability of water within the cell. A significant amount of water is bound in a 'hydration layer' around proteins, making it unavailable for other cellular processes. By clustering proteins into condensates, cells can effectively regulate the amount of free water versus bound water.

Key Strategies for Maintaining Water Balance

Here's a breakdown of how cells maintain water balance:

  • Biomolecular Condensates:

    • Proteins are organized into fluid assemblies.
    • This redistribution manages water availability.
  • Hydration Layer Regulation:

    • Water surrounding proteins in the 'hydration layer' is temporarily unavailable.
    • Cells control the balance between 'free' water and 'bound' water.

In essence, cells expertly manage the location and availability of water by altering the organization of their internal components. The formation and maintenance of biomolecular condensates play a significant role in maintaining cellular water balance.