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What is cell contact?

Published in Cellular Interactions 1 min read

Cell contact refers to the physical interaction between cells. This interaction plays a critical role in various biological processes, particularly within the immune system.

The Significance of Cell Contact

Cell contact is essential for:

  • Cell Communication: Facilitates direct signaling between cells.
  • Immune Response: Crucial for the activation of immune cells. For example, as highlighted in the reference, cell contact is vital for the activation of natural killer (NK) cells by dendritic cells (DCs) in the immune system.

Cell Contact in the Immune System: An Example

Let's look at the interaction between dendritic cells (DCs) and natural killer (NK) cells.

Cell Type Role
Dendritic Cells (DCs) Present antigens to other immune cells.
Natural Killer (NK) Cells Destroy infected or cancerous cells.

The physical contact between these cells allows DCs to activate NK cells, initiating an immune response against threats. This activation relies on specific molecules and receptors on the cell surfaces that bind to each other during cell contact.

Conclusion

Cell contact is not merely a touch; it is a dynamic interaction that governs cellular behavior and orchestrates complex biological functions, especially within the immune system.