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How Do Cells Repair?

Published in Cellular Repair 2 mins read

Cells repair themselves through a variety of mechanisms, depending on the type of cell and the extent of damage. The process often involves generating new cells to replace damaged ones, a direct consequence of a cell's ability to reproduce.

Cellular Repair Mechanisms

  • Self-Repair: Single cells, such as those studied in this research, initiate a self-repair response to damage. This involves initially stopping further damage and then rebuilding lost structures. For example, an overstretched cell will initiate a repair process rather than simply break.

  • Regeneration: Multi-cellular organisms often utilize regeneration, the process of creating new cells to replace damaged or lost ones. This is fundamentally linked to cell reproduction. Epithelial cells, for example, crawl from the basal layers into a wounded area to repair it. This study details the process.

  • Stem Cell Therapy: Stem cells, undifferentiated cells capable of becoming various specialized cell types, play a critical role in tissue repair. Stem cell therapy uses these cells to promote the repair of damaged or diseased tissue.

  • Cellular Maintenance and Repair: Specific cell types contribute to the maintenance and repair of organs, like the liver. Research has identified the specific cellular roles in liver regeneration after injury.

  • DNA Repair: Cells have mechanisms for repairing faults in their genes. Efficient DNA repair is crucial, as failures in this process can increase cancer risk. More information here.

The Importance of Protein

Protein plays a vital role in cellular repair. Amino acids, the building blocks of proteins, are essential for the body to repair existing cells and build new ones. More details on protein's role.

While some tissues, like the eye, currently lack the ability to regenerate cells in the body, research is ongoing to explore the possibility of creating replacement cells in the laboratory.