Lexie Grey was written off Grey's Anatomy primarily because the actress portraying her decided to leave the show.
When the actress chose to depart from the popular medical drama, the show's creator was tasked with devising a compelling storyline to explain Lexie's absence. This necessity led to a significant plot development that impacted multiple characters.
Notably, Lexie's exit profoundly influenced the fate of Mark Sloan. To maintain the narrative integrity of his character — given that he was portrayed as someone who would never abandon his child and would never truly move on from Lexie — his death became an inevitable consequence woven into the storyline following her departure. This connection highlights how Lexie's exit was not an isolated event but rather a catalyst for further critical developments within the series.
