Cisplatin is a platinum-based chemotherapy drug.
Cisplatin, also known as cisplatinum or cis-diamminedichloroplatinum(II) (CDDP), is a powerful medication utilized in chemotherapy to combat a variety of cancers. Its mechanism of action involves interfering with DNA replication in cancer cells, ultimately leading to cell death.
Cancers Treated with Cisplatin:
Cisplatin is commonly used to treat:
- Sarcomas
- Certain carcinomas, such as:
- Small cell lung cancer
- Ovarian cancer
- Lymphomas
- Germ cell tumors
Mechanism of Action (Simplified):
Cisplatin contains platinum. Once inside a cancer cell, it binds to DNA, distorting its structure. This distortion disrupts the process of DNA replication, which is essential for cancer cell division and growth. By interfering with DNA replication, cisplatin effectively stops cancer cells from multiplying, leading to their destruction.
Important Considerations:
While cisplatin is an effective cancer treatment, it can also cause side effects. These side effects can vary depending on the individual, the dosage, and the duration of treatment. Potential side effects include nausea, vomiting, kidney damage, hearing loss, and nerve damage. Careful monitoring and supportive care are crucial during cisplatin therapy to manage these potential side effects.
