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How is CSF tested?

Published in CSF Analysis 1 min read

Cerebrospinal fluid (CSF) is primarily tested through a procedure called a lumbar puncture, also known as a spinal tap, where the fluid is collected and then analyzed.

Lumbar Puncture Procedure Explained

The process involves carefully extracting a sample of CSF for laboratory analysis to detect diseases or injuries. Here’s a breakdown:

  • Needle Insertion: A needle is inserted, usually between the third and fourth lumbar vertebrae.
  • CSF Collection: Once the needle is correctly positioned, CSF fluid is collected.
  • Laboratory Analysis: The collected fluid is then sent to a lab for various tests.

What the Tests Look For

The tests performed on CSF can help diagnose a variety of conditions. Some common things the lab looks for include:

  • Infections: Bacteria, viruses, or fungi.
  • Inflammation: Elevated white blood cell count.
  • Bleeding: Presence of blood, which can indicate a hemorrhage.
  • Abnormal Proteins: Which might suggest certain neurological disorders.

Why is CSF Testing Important?

CSF analysis can provide vital clues to diagnose:

  • Meningitis
  • Encephalitis
  • Multiple sclerosis
  • Guillain-Barré syndrome
  • Subarachnoid hemorrhage
  • Certain cancers affecting the brain or spinal cord