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What is HHNk?

Published in Diabetes Complications 1 min read

HHNK refers to Hyperosmolar Hyperglycemic Nonketotic Coma, a serious complication primarily associated with type 2 diabetes. Because the question uses the acronym HHNk rather than HHNS (Hyperosmolar Hyperglycemic Nonketotic Syndrome) or HHS (Hyperosmolar Hyperglycemic State), coma is included in the definition.

Here's a breakdown:

  • Hyperosmolar: Indicates high concentration of solutes in the blood.
  • Hyperglycemic: Means high blood sugar levels.
  • Nonketotic: Implies an absence or minimal presence of ketones in the blood, unlike diabetic ketoacidosis (DKA).
  • Coma: Denotes a state of prolonged unconsciousness.

Most patients with HHNK require admission to the intensive care unit (ICU) due to the severity of the condition. This is because HHNK can lead to severe dehydration, electrolyte imbalances, and neurological dysfunction.

In summary, HHNK is a life-threatening condition arising from uncontrolled high blood sugar in individuals with type 2 diabetes, leading to hyperosmolarity and, ultimately, coma.