Household bleach, specifically sodium hypochlorite, effectively removes DNA from surfaces. Many scientific studies and laboratory practices utilize bleach for this purpose due to its proven efficacy. Other cleaning agents, such as certain acids at high temperatures, can also break down DNA, although bleach remains a commonly used and effective option. Note that some disinfectants may require a secondary wipe-down with water or ethanol to remove residue. Always follow the manufacturer's instructions carefully.
Effective DNA Removal Methods:
- Sodium Hypochlorite (Bleach): A highly effective and commonly used method for DNA removal. Multiple sources confirm its efficiency in eliminating DNA traces from surfaces. ([2], [1], [4])
- Acids (High Temperatures): Acids, particularly at elevated temperatures, can break down DNA. Citranox® Liquid Acid Cleaner is one example mentioned in research, but testing is recommended to determine efficacy. ([10])
Ineffective Methods:
- Ethanol (Alcohol): Ethanol is often used in DNA extraction, not for its DNA-destroying capabilities. It preserves DNA, not eliminates it. ([6])
Important Considerations:
- Surface Type: The effectiveness of any cleaning agent depends on the surface material. Always check compatibility before using any cleaner. ([8])
- Safety Precautions: Always follow the manufacturer's instructions and take necessary safety precautions when using any cleaning agent, including wearing appropriate personal protective equipment. ([5], [8])
- Incompatible Cleaners: Never mix incompatible disinfectants, such as bleach and ammonia, as this can produce toxic gases. ([2])
