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What Can Remove DNA?

Published in DNA Removal 2 mins read

Several methods and substances can remove or destroy DNA. This includes chemical agents, physical processes, and legal procedures for removing DNA records.

Chemical Removal of DNA

Certain chemicals are highly effective at degrading or destroying DNA. Examples include:

  • Bleach (sodium hypochlorite): Studies show bleach, both fresh and stored, is very efficient at DNA removal, achieving near-complete removal from various surfaces.[1]
  • Trigene®: This commercial product is also highly effective at removing DNA.[1]
  • Virkon®: This disinfectant demonstrates a high DNA removal ability, making it a suitable option for decontaminating instruments.[2]

Other agents capable of damaging DNA include mycotoxins, rusted iron, excessive heat, and UV radiation.[3]

Physical and Enzymatic Removal of DNA

Beyond chemical methods, physical processes and enzymes can affect DNA:

  • DNase Treatment: Specific enzymes, like DNases, can be used to break down DNA molecules in RNA preparations without harming the RNA itself. This is a crucial step in RNA purification.[4]
  • Washing buffers containing alcohol: These are often used in DNA purification protocols to remove impurities and contaminants.[5]

Legal Removal of DNA Records

Removing DNA from databases and official records is a legal process that varies depending on jurisdiction. Requests for removal are handled differently depending on the location and the reason for the DNA collection. For example:

  • Indiana: Indiana residents can request removal from their DNA database under certain conditions (following state law).[6]
  • Colorado: Colorado has specific qualifications and instructions for the removal of arrestee DNA samples from their database.[7]
  • Other Jurisdictions: Procedures for removing DNA or fingerprint data from police records vary across different jurisdictions. Some may offer the possibility of deletion or modification of certain data.[8, 9]

This process usually requires submitting a formal request and complying with specific guidelines and regulations.

[1] Evaluation of Different Cleaning Strategies for Removal of… (ncbi.nlm.nih.gov)
[2] Evaluation of Different Cleaning Strategies for Removal of… (ncbi.nlm.nih.gov)
[3] What can destroy DNA evidence? - Quora
[4] A NEW Method to Remove DNA | Thermo Fisher Scientific - US
[5] DNA Purification | DNA Extraction Methods | Promega
[6] ISP: ISP Labs: Request for Removal from the DNA Database
[7] DNA Database Expungement | Colorado Bureau of Investigation
[8] I want my DNA or fingerprints removed from police records ...
[9] I want my DNA or fingerprints removed from police records ...