Protamine, specifically protamine sulfate, begins to work very quickly, with an onset of action typically observed within 5 minutes of administration. This rapid response is crucial in clinical scenarios where immediate reversal of anticoagulant effects is necessary.
Protamine sulfate is primarily used to counteract the anticoagulant effects of heparin, a medication that prevents blood clotting. Its quick action makes it an essential agent in emergency situations, such as after surgical procedures where heparin was used, or in cases of heparin overdose. The prompt onset ensures that bleeding can be controlled effectively and efficiently.
Clinical Data for Protamine Sulfate
The swiftness of protamine's effect is a key characteristic that makes it valuable in medical practice. For more detailed information on this medication, you can refer to resources like Protamine sulfate on Wikipedia.
| Clinical Parameter | Value |
|---|---|
| Onset of Action | 5 minutes |
| CAS Number | 9009-65-8 |
| DrugBank ID | DB09141 |
This immediate therapeutic effect allows healthcare professionals to quickly manage bleeding risks, particularly during and after procedures like cardiac surgery, dialysis, or in cases of bleeding complications related to heparin therapy.
