The exact percentage of embryos that come back normal after Preimplantation Genetic Testing (PGT-A) varies significantly with the individual's age at the time of egg retrieval. PGT-A, or preimplantation genetic testing for aneuploidies, screens embryos for chromosomal abnormalities before implantation during an IVF cycle.
The likelihood of having a chromosomally normal embryo decreases as a person ages. This is a crucial factor in fertility treatment outcomes.
Here's a breakdown of the approximate percentages of embryos found to be chromosomally normal after PGT-A, categorized by age:
| Age Range | Percentage of Normal Embryos |
|---|---|
| Under 35 years old | 72% |
| 35-37 years old | 62% |
| 38-40 years old | 46% |
| 41-42 years old | 30% |
Understanding PGT-A Results
PGT-A helps identify embryos with the correct number of chromosomes (euploid embryos), which are generally considered the most viable for transfer. Embryos with an abnormal number of chromosomes (aneuploid embryos) are the primary reason for IVF cycle failures, miscarriages, and certain genetic conditions.
- Impact of Age: The decline in normal embryo percentages with increasing maternal age is primarily due to the natural aging process of eggs, which can lead to errors during cell division.
- Benefits of PGT-A: While PGT-A doesn't increase the number of normal embryos, it helps in selecting the healthiest available embryos, which can improve the chances of a successful pregnancy and reduce the risk of miscarriage. For more in-depth information on PGT-A and its role in IVF, you can refer to resources like fertilityspace.io.
It's important to remember that these percentages are averages, and individual results can vary based on a variety of factors, including egg quality, sperm quality, and specific clinical circumstances.
