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Does Albinism Affect Eye Color?

Published in Eye Genetics 2 mins read

Yes, albinism significantly affects eye color. Albinism is a genetic condition that reduces or prevents the production of melanin, the pigment responsible for color in skin, hair, and eyes. This lack of melanin leads to characteristically light-colored eyes.

How Albinism Impacts Eye Color:

  • Reduced Melanin: The most crucial factor is the deficient melanin production. Melanin provides the brown, green, or hazel hues to the iris (the colored part of the eye). With less melanin, the iris appears lighter, often resulting in blue eyes.

  • Visible Blood Vessels: In many cases, the reduced pigmentation allows the blood vessels behind the iris to be more visible. This can give the eyes a pinkish or reddish appearance, especially under certain lighting conditions. This is particularly true in individuals with ocular albinism.

  • Varied Eye Color: While many individuals with albinism have light-colored eyes, the exact shade can vary. The degree of melanin deficiency differs between individuals and types of albinism, leading to a range of eye colors from light blue to pink or red.

  • Ocular vs. Oculocutaneous Albinism: The impact on eye color also depends on the specific type of albinism. Ocular albinism primarily affects the eyes, while oculocutaneous albinism impacts eyes, skin, and hair, typically resulting in very light skin and hair alongside light-colored eyes.

Several sources confirm this: Most individuals with ocular albinism have blue eyes, but the underlying blood vessels can make the eyes look pink or red (WebMD, [Source referencing Nov 9, 2022]). Oculocutaneous albinism is characterized by light-colored irises (MedlinePlus Genetics). Although lighting conditions can affect the appearance, making eyes seem reddish or violet, most individuals with albinism have light-colored eyes (National Organization for Albinism and Hypopigmentation). The lack of pigment in albinism prevents normal eye development, affecting vision and eye color (AllAboutVision).