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Can You Be Allergic to Onions?

Published in Food Allergy 2 mins read

Yes, you can be allergic to onions. While an onion allergy is uncommon, it's a genuine allergic reaction affecting people of all ages. The immune system mistakenly identifies onions (and sometimes other alliums) as harmful, triggering an allergic response.

Understanding Onion Allergies

  • Rarity: Onion allergies are relatively rare. One study found that approximately 30% of 8109 allergic patients showed sensitivity or clinical symptoms related to onions. [Source: Thermo Fisher Scientific]
  • Allergens: The main allergens in onions include All c 3 (a lipid transfer protein), All c 4 (a profilin), and Allin lyase. [Source: Provided reference text]
  • Cross-Reactivity: People with onion allergies may also react to other members of the allium family, such as garlic, chives, scallions, leeks, and shallots. The severity of the cross-reaction can vary. [Source: Provided reference text, Anaphylaxis UK, Have A Plant] For example, someone who tolerates garlic might still react to leeks. [Source: Have A Plant]
  • Symptoms: Allergic reactions can range from mild (itching, hives, swelling) to severe (anaphylaxis, difficulty breathing). [Source: Healthline, Medical News Today, Wyndly]
  • Diagnosis: A blood test (specifically a CAP certified ELISA methodology test) is the most reliable way to diagnose an onion allergy. [Source: Quora]
  • Treatment: Avoiding onions and related alliums is crucial. For severe reactions, emergency medical treatment may be necessary. [Source: Cleveland Clinic]

Substituting Onions in Cooking

If you have an onion allergy, finding substitutes is important. Good options include:

  • Leeks (but be cautious due to cross-reactivity)
  • Garlic (also an allium, so use cautiously)
  • Shallots (also an allium, so use cautiously)
  • Celery
  • Carrots
  • Mushrooms

The best substitute depends on the specific dish and desired flavor.