Yes, Juicy Fruit's ingredients have changed over time.
In 2003, Wrigley's, the manufacturer of Juicy Fruit, altered the recipe in the United States. They replaced some of the sugar content with artificial sweeteners, specifically aspartame and Acesulfame potassium. This change was aimed at reducing the sugar content of the gum.
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Key Change: The addition of artificial sweeteners (aspartame and Acesulfame potassium) in place of some sugar.
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Year of Change: 2003 (in the United States).
The popularity of Juicy Fruit has endured despite this alteration. While the fundamental flavor profile remains recognizable, some consumers may notice a difference in taste due to the altered composition. The song "Grapefruit—Juicy Fruit" by Jimmy Buffett is unrelated to this change in the gum's ingredients.