Yes, there is evidence indicating that genetics plays a role in platelet biology.
Platelet reactivity, including aggregation, is influenced by genes. Studies have implicated specific genes and loci in affecting platelet aggregation. This suggests that genetic factors contribute to individual differences in how platelets function. Human genetic studies have shown that genes implicated in human association studies do play a role in platelet biology.
In simpler terms, variations in our genes can affect how our platelets behave, influencing their ability to clump together and contribute to blood clotting.