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What is the 9 3 3 1 rule?

Published in Genetics 1 min read

The 9:3:3:1 ratio is a phenotypic ratio observed in the offspring of a dihybrid cross. This means that two individuals who are heterozygous for two genes are being crossed. For example, AaBb x AaBb. This ratio indicates the different combinations of traits expressed in the offspring.

Here's how it works:

  • 9: Represents the number of offspring expressing the dominant allele for both genes.
  • 3: Represents the number of offspring expressing the dominant allele for one gene and the recessive allele for the other.
  • 3: Represents the number of offspring expressing the recessive allele for one gene and the dominant allele for the other.
  • 1: Represents the number of offspring expressing the recessive allele for both genes.

Example:

Consider two pea plants, both heterozygous for seed shape (Round, R, dominant over Wrinkled, r) and seed color (Yellow, Y, dominant over Green, y).

  • Parental genotypes: RrYy x RrYy
  • Offspring phenotypes:
    • 9 Round Yellow
    • 3 Round Green
    • 3 Wrinkled Yellow
    • 1 Wrinkled Green

Practical Insights:

  • This rule is fundamental in understanding inheritance patterns and predicting offspring traits.
  • It is used extensively in genetics and breeding programs, helping to select for desirable traits.
  • The 9:3:3:1 ratio demonstrates the independent assortment of genes, meaning that alleles of different genes separate independently during gamete formation.