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Is an Amine Hormone Derived from Serotonin?

Published in Hormone Biochemistry 1 min read

No, an amine hormone is not derived from serotonin. Serotonin itself is an amine hormone, and it is derived from the amino acid tryptophan.

Amine Hormones and Serotonin's Origin

Amine hormones are a class of hormones that are synthesized from single amino acids. These amino acids are modified to create hormones with an amine group (-NH2). Examples of amine hormones include:

  • Catecholamines (epinephrine, norepinephrine, dopamine): Derived from tyrosine.
  • Serotonin: Derived from tryptophan.
  • Histamine: Derived from histidine.

Serotonin's synthesis pathway begins with the amino acid tryptophan. Tryptophan is converted into 5-hydroxytryptophan, which is then converted into serotonin (5-hydroxytryptamine).

Key Takeaway

Serotonin is itself an amine hormone derived from tryptophan, not the source from which other amine hormones are created.