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What is human skin made of?

Published in Human Anatomy 1 min read

Human skin is the largest organ in the body, acting as a protective barrier against the environment. It is composed of multiple layers and is primarily made of water, proteins, and fats.

  • Water: Makes up about 70% of the skin's composition.
  • Proteins: Account for around 25% of the skin, with collagen being the most abundant protein. Collagen provides strength and elasticity, while keratin helps create a tough outer layer.
  • Lipids: Contribute about 3% of the skin's composition, forming a protective barrier and keeping it moisturized.
  • Other Components: Minerals, nucleic acids, glycosamines, and proteoglycans are also present in smaller amounts.

The skin is divided into three main layers:

  • Epidermis: The outermost layer, responsible for protection and acting as a barrier against infection.
  • Dermis: The middle layer, containing blood vessels, nerves, hair follicles, and sweat glands.
  • Hypodermis: The innermost layer, primarily made of fat and connective tissue, providing insulation and cushioning.

The skin also hosts a diverse community of microorganisms called the skin microbiome. These microbes play a role in skin health and immunity.