The liver is insensitive to pain. This means that the liver itself does not have pain receptors, so it cannot feel pain even when damaged.
This insensitivity is also shared by the alveoli of the lungs, the tiny air sacs where gas exchange occurs. These organs are not equipped to register pain despite potential injury or irritation.
This lack of pain perception in the liver and alveoli is due to the absence of nociceptors, the specialized sensory neurons that detect pain.
While the liver and alveoli are insensitive to pain, it's important to remember that visceral pain can be felt from other organs like the intestines, stomach, and gallbladder. This type of pain can be difficult to pinpoint because it can radiate to other areas of the body.
It's also worth noting that congenital insensitivity to pain (CIPA) is a rare genetic disorder that affects the ability to perceive pain. People with CIPA lack the ability to feel pain in any part of their body, making them vulnerable to serious injuries.
