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What is the first line of treatment for IBD?

Published in IBD Treatment 2 mins read

The first line of treatment for mild to moderate Inflammatory Bowel Disease (IBD), specifically ulcerative colitis, often involves anti-inflammatory drugs.

Understanding First-Line Treatment for IBD

When someone is diagnosed with IBD, particularly ulcerative colitis, the initial treatment approach usually focuses on reducing inflammation in the digestive tract. Here's a breakdown:

  • Anti-inflammatory Medications: These drugs are designed to target the inflammatory process that is central to IBD.

    • Aminosalicylates: These are a common type of anti-inflammatory, and include medications such as:

      • Mesalamine (available under brand names like Delzicol, Rowasa)
      • Balsalazide (Colazal)
      • Olsalazine (Dipentum)
    • These drugs are often prescribed as a first line of defense against the inflammation associated with ulcerative colitis.

How These Medications Work

  • Mechanism of Action: Aminosalicylates work directly in the gut to reduce inflammation, providing relief from symptoms like abdominal pain, diarrhea, and rectal bleeding.
  • Forms of Medication: They are available in various forms, including oral pills, suppositories, and enemas, allowing for targeted treatment based on the location and severity of the inflammation.

Key Points

  • The information provided applies specifically to the treatment of mild to moderate ulcerative colitis.
  • The selection of medication and treatment plan should always be made in consultation with a healthcare provider.
  • While anti-inflammatory drugs are often the first step, other treatments may be necessary depending on disease severity and individual responses.