The International Classification of Diseases, Tenth Revision (ICD-10) code specifically assigned for a selective deficiency of immunoglobulin G (IgG) subclasses is D80.3.
Understanding IgG and ICD-10 Codes
Immunoglobulin G (IgG) is the most abundant type of antibody in the human body, playing a vital role in the immune system's defense against a wide range of pathogens, including bacteria, viruses, and fungi. While IgG is a normal and crucial component of immunity, ICD-10 codes are used to classify and report diseases, disorders, signs, symptoms, and other health-related conditions. Therefore, an ICD-10 code associated with IgG refers to a medical condition or abnormality involving IgG, such as a deficiency.
The Specific ICD-10 Code: D80.3
The code D80.3 precisely identifies a medical condition characterized by insufficient levels of one or more IgG subclasses. This selective deficiency means that while total IgG levels might be normal, specific subclasses (like IgG1, IgG2, IgG3, or IgG4) are below the typical range.
Breakdown of the Code
| ICD-10 Code | Description | Category |
|---|---|---|
| D80.3 | Selective deficiency of immunoglobulin G [IgG] subclasses | D80: Immunodeficiency with predominant antibody defects |
Clinical Significance of D80.3
A diagnosis of selective IgG subclass deficiency often carries important clinical implications, primarily an increased susceptibility to infections.
- Diagnosis of Selective IgG Subclass Deficiency:
- This condition is typically suspected in individuals, especially children, who experience recurrent or unusually severe infections, particularly affecting the respiratory tract (e.g., recurrent pneumonia, sinusitis, otitis media).
- Diagnosis involves specialized blood tests to measure the levels of each specific IgG subclass. It's crucial to differentiate this condition from other primary immunodeficiencies.
- Management and Treatment:
- Infection Prevention: Strategies often include prompt and aggressive treatment of infections, and sometimes long-term prophylactic antibiotics to prevent recurrent episodes.
- Immunoglobulin Replacement Therapy: In cases where the deficiency is severe and leads to significant morbidity, immunoglobulin replacement therapy (e.g., intravenous immunoglobulin (IVIG) or subcutaneous immunoglobulin (SCIG)) may be considered to bolster the patient's immune defenses.
- Monitoring: Regular monitoring of IgG subclass levels and clinical symptoms is important to manage the condition effectively.
For more detailed information on this specific code and its implications, you can consult official medical coding resources.
