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What are NK cells?

Published in Immune Cell Type 2 mins read

Natural killer (NK) cells are a critical part of the immune system. They are a type of white blood cell and a type of lymphocyte that are vital for fighting off disease.

Key Characteristics of NK Cells

  • White Blood Cells: NK cells are classified as white blood cells, which means they are involved in immune responses.
  • Lymphocytes: They belong to the lymphocyte family, along with B-cells and T-cells.
  • Destroy Infected and Diseased Cells: Their primary function is to eliminate cells that are infected or have become cancerous.

How NK Cells Function

NK cells act as an early defense system in the body. They can identify and destroy harmful cells before they have a chance to spread. Here's a breakdown of their key actions:

  • Early Detection: NK cells patrol the body, identifying cells that exhibit markers of infection or cancerous transformation.
  • Direct Destruction: They kill compromised cells directly. This prevents the spread of viruses and stops tumor development at the earliest stages.
  • Prevention of Spread: By eliminating abnormal cells quickly, NK cells help to keep diseases from taking hold and spreading.

Comparison with Other Immune Cells

While B-cells and T-cells are also lymphocytes, NK cells have a different approach to fighting disease.

Feature NK Cells B-Cells T-Cells
Main Function Destroy infected and cancerous cells directly Produce antibodies Target and kill infected cells
Mechanism Direct cellular killing Antibody-mediated immune responses Cell-mediated immune responses
Type Part of the innate immune system Part of the adaptive immune system Part of the adaptive immune system

Examples of NK Cell Action

  • Viral Infections: During a viral infection, NK cells quickly identify and destroy virus-infected cells, preventing the virus from replicating and causing further damage.
  • Cancer: NK cells are vital in cancer surveillance, where they detect and eliminate early cancer cells before a tumor can form.

In summary, NK cells are crucial for maintaining health by acting as the first line of defense against infections and cancer. They efficiently target and destroy dangerous cells without prior sensitization.