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Which immunoglobulin is present in infection?

Published in Immune Response 2 mins read

During an infection, one of the key antibodies produced by the body, particularly in the early stages, is Immunoglobulin M (IgM).

Understanding IgM in the Immune Response

The immune system defends the body against invaders like bacteria and viruses by producing specific antibodies. As highlighted by the reference:

Immunoglobulin M (IgM) IgM antibodies are the main immunoglobulin species involved in the primary immune response, being produced early in the course of an infection. IgM species does not reemerge during secondary immune responses (11).

This information tells us several key things about the presence and role of IgM during an infection:

  • Early Responder: IgM antibodies are among the first antibodies to appear when the body encounters a new pathogen. They are produced early in the infection timeline.
  • Primary Immune Response: IgM is the primary immunoglobulin involved in the body's initial reaction to an infection. This is the "primary immune response."
  • Not a Late/Memory Responder: Unlike some other antibodies (which are not discussed in the provided reference), IgM does not reappear during subsequent encounters with the same pathogen (secondary immune responses).

In summary, based on the provided reference, Immunoglobulin M (IgM) is a significant antibody present during an infection, playing a crucial role in the body's initial defense mechanism.