What Do Interleukins Attract?

Interleukins are a group of signaling proteins that play crucial roles in the immune system, particularly in coordinating the response to inflammation and infection. While the term "interleukins" encompasses a broad family of molecules with diverse functions, specific interleukins act as chemotactic factors, meaning they attract certain types of cells to a particular location, such as a site of inflammation or injury.

Focus on Interleukin 8 (IL-8)

Based on the provided reference, Interleukin 8 (IL-8) is a well-known example of an interleukin that acts as a chemotactic factor. During the inflammatory process, IL-8 signals to and attracts specific types of immune cells to the affected area.

According to the reference:

• Interleukin 8 (IL-8) is a chemotactic factor that attracts the following cell types:
  • Neutrophils: These are the most abundant type of white blood cell and are typically the first responders to bacterial infections and inflammation.
  • Basophils: These are a type of granulocyte involved in the immune response, particularly in allergic reactions and parasitic infections.
  • T-cells: These are a type of lymphocyte critical for cell-mediated immunity, including recognizing and destroying infected cells.

It is also important to note what IL-8, specifically according to the reference, does not attract:

• The reference states that IL-8 is not a chemotactic factor for monocytes. Monocytes are another type of white blood cell that differentiates into macrophages and dendritic cells at the site of inflammation.

In summary, based on the provided information about IL-8:

This specific attraction of immune cells by IL-8 is a key part of the body's defense mechanism, helping to clear pathogens and initiate tissue repair at the site of inflammation.