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Why Am I Feeling Pain After Injection?

Published in Injection Site Pain 2 mins read

Pain after an injection is a common reaction. It's often a result of the needle itself or a response to the injected medicine, or both. This reaction can occur immediately or develop later.

Understanding Post-Injection Pain

The most frequent cause of pain after an injection is a localized reaction at the injection site. This is due to:

  • Needle Trauma: The needle's puncture of the skin and underlying tissue causes minor inflammation and irritation.
  • Medication Response: The injected substance can cause irritation or inflammation. This is a normal part of the body's response to a foreign substance. The immune system is triggered, causing the release of inflammatory chemicals leading to swelling, pain, and tenderness.

Different injections may lead to varying levels and types of pain. For example:

In rare instances, post-injection pain could indicate an infection at the site. Signs of infection include increased pain, swelling, redness, and warmth at the injection site. Source: Saint Luke's Health - Understanding Post-Injection Inflammation

When to Seek Medical Attention

While mild pain and swelling are normal, severe pain, or other symptoms like:

  • Persistent, worsening pain
  • Swelling that increases significantly
  • Redness or warmth extending beyond the injection site
  • Fever
  • Pus or drainage from the injection site
  • Allergic reactions (such as difficulty breathing, hives, or swelling of the face, lips, or tongue)

should prompt a call to your healthcare provider. Source: Verywell Health - When to Call Your Healthcare Provider About an Injection Side Effect