To mix an insulin infusion, follow these steps using the information from the provided reference:
The standard approach for mixing an intravenous insulin infusion is to prepare a solution of 1 unit of regular human insulin per milliliter (1 U/mL).
Here's a breakdown of the process:
Insulin Infusion Preparation
- Step 1: Gather Supplies
- 250 units of regular human insulin
- 250 mL of normal saline solution
- Appropriate intravenous infusion bag
- Step 2: Combine Insulin and Saline
- Mix the 250 units of regular human insulin with the 250 mL of normal saline solution in the intravenous infusion bag. This creates a solution with a concentration of 1 U/mL.
Important Considerations:
- Priming the Line:
- Before initiating the infusion, flush approximately 30 mL of the insulin solution through the intravenous line. This ensures the line is primed with insulin and delivers the correct dose to the patient.
- Avoid Filters:
- Do not use a filter or filtered set with insulin infusions, as the filter can bind to the insulin and reduce the delivered dose.
- Infusion Method:
- Use an intravenous infusion pump with a capability of 0.1 mL/hr for accurate delivery.
- Piggyback the insulin drip into the patient's main intravenous fluid line.
Practical Insights:
- Concentration Consistency:
- Using the 1 U/mL ratio simplifies dosing calculations and reduces medication errors.
- Regular Insulin:
- Ensure that regular human insulin is used for IV infusions, as other insulin types are not suitable.
- Monitoring:
- Closely monitor the patient's blood glucose levels throughout the insulin infusion.
- Preparation:
- Prepare the solution in an appropriate setting and follow sterile technique.
- Storage:
- Prepare the insulin infusion solution immediately before administration. If necessary, store under appropriate conditions as recommended by the manufacturer.
By following these steps, healthcare professionals can safely and effectively administer insulin infusions.
