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Is Insulin A or B?

Published in Insulin Structure 1 min read

Insulin is neither A nor B; it is a protein composed of both an A chain and a B chain.

Understanding Insulin's Structure

Insulin's structure is vital to its function. It's not simply "A" or "B" but a combination of the two. Here's a breakdown:

  • The A Chain: This chain consists of 21 amino acids.
  • The B Chain: This chain is slightly longer, containing 30 amino acids.
  • Linkage: The A and B chains are linked together by sulfur atoms, forming the complete functional insulin molecule.
  • Origin: Insulin is derived from a precursor molecule called proinsulin, which contains 74 amino acids. The proinsulin is processed to form the mature insulin with its A and B chains.

Key Details from Britannica

According to Britannica, Insulin is a protein consisting of two chains: the A chain with 21 amino acids and the B chain with 30 amino acids. These chains are connected by sulfur atoms.


Component Description
A Chain 21 amino acids
B Chain 30 amino acids
Linkage Sulfur atoms
Precursor Proinsulin (74 amino acids)

Therefore, it's more accurate to say that insulin is made up of both an A and B chain rather than being one or the other.