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How do you make intravenous fluids?

Published in IV Fluid Preparation 1 min read

The provided reference describes a specific example of adjusting a pre-existing intravenous fluid solution, not a general method for creating IV fluids from scratch. Therefore, it describes compounding or modifying an existing IV solution rather than a de novo creation. Here's how the reference describes modifying an existing IV fluid bag:

To modify an existing IV fluid bag of 500ml 0.45% Sodium Chloride 5% glucose solution:

  1. Remove and discard 56 ml from the 500ml bag of 0.45% Sodium Chloride 5% glucose.
  2. Add 56ml of 50% glucose to the remaining bag.
  3. Add 7.5ml of concentrated 30% sodium chloride, measuring very carefully.

This procedure illustrates how specific IV fluid formulations can be adjusted. In this example, the concentrations of glucose and sodium chloride are being altered.