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What Causes the Whites of Your Eyes to Turn Yellow?

Published in Jaundice Causes 3 mins read

The whites of your eyes, medically known as the sclera, primarily turn yellow due to a condition called jaundice. This distinct yellow discoloration is a visible indicator that there is an excessive buildup of a yellowish pigment called bilirubin in the bloodstream and tissues of the body.

Understanding Jaundice: The Primary Cause of Yellow Eyes

When the entire sclera takes on a yellow hue, it is frequently a significant sign of jaundice. It's important to understand that jaundice itself is not a disease but rather a symptom that signals an underlying issue with how your body processes or eliminates bilirubin.

The Role of Bilirubin in Your Body

Bilirubin is a yellowish byproduct that naturally forms when old red blood cells break down. Under normal circumstances, your body has an efficient system for managing this pigment:

  • The liver plays a crucial role, responsible for filtering bilirubin from the blood.
  • Once filtered, the liver processes this bilirubin, transforming it into bile.
  • This bile is then stored in the gallbladder, awaiting release.
  • Ultimately, the bile is released into the small intestine, assisting in digestion, and is then excreted by the body, primarily through stool.

When any part of this intricate process is disrupted—whether due to an impaired liver, blockages in the bile ducts, or an abnormally rapid breakdown of red blood cells—bilirubin can accumulate to high levels in the blood. When these levels become excessive, the yellow pigment begins to deposit in various body tissues, most noticeably in the whites of the eyes, causing the characteristic yellow appearance.

Common Reasons for Bilirubin Buildup Leading to Jaundice

Several conditions can lead to an accumulation of bilirubin, resulting in jaundice and the yellowing of the eyes. These typically relate to problems within the bilirubin processing pathway:

  • Liver Diseases: Conditions such as hepatitis (inflammation of the liver), cirrhosis (scarring of the liver), or liver failure can severely impair the liver's ability to filter and process bilirubin effectively.
  • Gallbladder or Bile Duct Issues: Obstructions like gallstones or tumors in the bile ducts can block the flow of bile (which contains processed bilirubin), causing it to back up into the bloodstream.
  • Excessive Red Blood Cell Breakdown: Certain blood disorders, such as hemolytic anemia, cause red blood cells to break down at an accelerated rate. This rapid breakdown produces more bilirubin than the liver can handle, leading to an overload.
  • Other Causes: Less commonly, certain medications, genetic conditions like Gilbert's syndrome, or rare diseases can also contribute to elevated bilirubin levels and jaundice.

When to Seek Medical Attention for Yellow Eyes

If you observe the whites of your eyes turning yellow, it is vital to seek prompt medical attention. Jaundice is not merely a cosmetic issue; it is a significant symptom indicating an underlying health problem that requires professional diagnosis and appropriate treatment. A healthcare provider can conduct necessary tests to pinpoint the exact cause of the bilirubin buildup and guide you on the best course of action.