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What is Poor Man's Dialysis?

Published in Kidney Dialysis 3 mins read

"Poor man's dialysis" is an informal term sometimes used to refer to Sustained Low-Efficiency Dialysis (SLED), also known as Prolonged Intermittent Renal Replacement Therapy (PIRRT). It is a hybrid form of dialysis designed to combine the advantages of traditional intermittent hemodialysis (IHD) with those of continuous renal replacement therapy (CRRT).

Understanding SLED (Sustained Low-Efficiency Dialysis)

SLED is a dialysis modality primarily used in critically ill patients, particularly those in intensive care units (ICUs) who may not tolerate the rapid fluid and solute shifts of conventional intermittent hemodialysis but do not necessarily require or have access to continuous renal replacement therapy.

  • Hybrid Approach: SLED integrates aspects of both intermittent hemodialysis (IHD) and continuous renal replacement therapy (CRRT). It is performed for longer durations than typical IHD sessions (e.g., 8-12 hours) but is not continuous like CRRT.
  • Balanced Removal: By using lower blood and dialysate flow rates than IHD but for extended periods, SLED aims to achieve effective solute and fluid removal while minimizing the hemodynamic instability often seen with rapid, short-duration treatments. This makes it particularly suitable for patients who are hemodynamically unstable.

Why is it Called "Poor Man's Dialysis"?

The colloquial term "poor man's dialysis," or "poor man's CRRT," highlights its practical advantages, particularly in terms of resource utilization. While CRRT requires dedicated, specialized equipment and continuous staffing, SLED can often be performed using standard intermittent hemodialysis machines, albeit with adjusted settings. This makes it a more cost-effective and logistically simpler alternative to CRRT in many clinical settings, especially where CRRT resources are limited.

Key Aspects of SLED

SLED aims to provide a middle ground between the two primary dialysis modalities, offering a flexible and effective treatment option:

  • Takes the Best Parts: It seeks to leverage the benefits of intermittent hemodialysis (e.g., using widely available machines, less complexity in setup compared to CRRT) and continuous RRT (e.g., slower, more gentle removal of fluids and toxins, better hemodynamic tolerability for unstable patients).
  • Flexibility: Sessions can be tailored in terms of duration and frequency, allowing clinicians to customize treatment based on patient needs and tolerance.
  • Clinical Application: Often chosen for patients with acute kidney injury (AKI) who are hemodynamically unstable, or in situations where CRRT is unavailable or impractical.

Here's a simplified comparison of renal replacement therapies:

Modality Duration Characteristics
Intermittent Hemodialysis (IHD) 3-5 hours, 3-4 times/week Rapid solute/fluid removal, can cause hemodynamic instability.
Continuous Renal Replacement Therapy (CRRT) 24 hours/day (continuous) Slow, gentle removal, ideal for hemodynamically unstable patients, resource-intensive.
Sustained Low-Efficiency Dialysis (SLED) / PIRRT 6-12 hours, daily or every other day Hybrid: Slower than IHD, less continuous than CRRT. Better tolerated than IHD for unstable patients, less resource-intensive than CRRT.

For further reading on critical care nephrology and various renal replacement therapies, you can consult medical resources such as Medscape.